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深圳湾实验室转化医学研究所招聘信息

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转化医学研究所简介

践行"健康中国"战略,针对中国市场打造生命科学与生物医药产业链,推动粤港澳大湾区创新基地建设。借助斯克瑞普斯研究所"从实验到临床"的成功模式,在深圳创办创新药物研发与推广平台。

筛选系统及化合物库建设:建立全自动超高通量筛选系统(uhts),具有苗头分子分拣和化合物管理功能;建立一系列独有的,定制的大型的化合物库,总的化合物数量在一百万个左右;建立基于calibr的reframe库,重新建立一个包含15000多种化合物的药物再开发化合物库。

实验平台建设:体外生物学实验室;药物化学实验室;蛋白质治疗实验室;药理学实验室。

蛋白组学质谱应用工程师

一、岗位工作内容

1、负责蛋白质组学样品制备(包括各种样品前处理方法和酶解等)、液相色谱串联质谱分析,以及质谱相关操作方法的优化开发;

2、负责基于质谱的蛋白组学数据处理与分析,包括数据库搜索等;

3、负责培训并指导实验人员完成相关实验操作;

4、负责蛋白组学质谱的日常维护保养;

5、其它岗位相关工作。

二、应聘条件

1、硕士及以上学历;

2、分子生物学、生物化学、分析化学、细胞生物学等专业,有蛋白质组学相关项目研究背景;

3、对蛋白质组学有深入了解和研究,熟练掌握蛋白质组学相关的理论、方法和应用,熟悉蛋白质组学相关数据库及相关分析软件,熟悉蛋白质组学数据的统计与分析;

4、良好的英语阅读及表达能力,有较强学习能力、沟通能力及团队协作精神。

三、工作条件和待遇

1、单位提供具有竞争力的薪资待遇,具体薪资和职位面议;

2、符合条件的申请人可申请深圳市相关配套待遇(如孔雀计划等),深圳湾实验室可协助进行申请。

四、应聘者请提供以下材料

1、个人简历;

2、《深圳湾实验室职位申请表》(见附件)

五、应聘程序

1.提交简历等材料:应聘者请将应聘材料发送至招聘专用邮箱:,请在邮件主题中标明“深圳湾实验室+岗位名称+姓名”。招聘小组在收到简历后,将通过电话以及邮件发送面试邀请。

2.招聘考核及考核结果发布:招聘考核分为资格审查、专家面试等环节。面试通过后即发布录用通知。

六、联系人

联系人:王老师;

电话:0755-26653579;

email:

附件:

hts engineer

position overview:

automation engineer/head of high throughput screening

shenzhen bay laboratory is seeking a talented automation engineer/head to lead the automation and high throughput screening group. the individual would be responsible for running, managing and maintaining laboratory automation as well as biochemical and cell-based assay development for hts. a successful candidate will have experience in lab automation, screening and assay development.

specialization in one or more the following is highly desirable: cell-based and biochemical assay development, high content imaging and flow cytometry or programming in java, c# or related languages. we are looking for someone who truly enjoys working with technology, so candidates with recreational interest in programming, auto repair, arduino devices, etc. may be an especially good fit.

essential duties and responsibilities:

• operate, maintain and troubleshoot uhts system

• assay development, optimization and miniaturization

• troubleshooting screening issues related to both automation and assay conditions

• continual improvement of technologies through innovation

• data analysis of high throughput screens.

qualifications and experience:

requirements

• ms or phd degree in engineering, biology or a relevant field with 2-5 years of experience in lab automation and screening.

• assay development of biochemical and cell-based assays

• experience running and troubleshooting lab automation including but not limited to liquid handling, acoustic dispensers, multi-mode readers, compound transfer devices, etc.

• ability to troubleshoot equipment problems and perform quality testing.

• working with teams to transition an assay from the bench to a high throughput screen.

• able to collaborate proficiently and communicate effectively with colleagues and management

• high level of self-motivation.

experience in one or more of the following is highly desirable

• programming in java, c#, javascript and other languages

• programming and operation of the labcyte echo and access system, agilent bravo, tecan freedom evo, bmg pherastar multi-reader, larger multi station-based systems such as highres and gnf systems.

• high content imaging and or flow cytometry

• cell based and biochemical assay development

• statistical analysis and/or design of experiment

compensation and salary: $100k to $150k/y

purpose of the initial working period at calibr, scripps research:

• learn the cutting-edge technologies in uhts systems

• help design the state of the art ultra hts systems that fit the best need of the new institute in shenzhen

• work with the vendors from various suppliers to assemble and integrate the uhts system

• build-up first-hand experience in daily operation and maintenance, data acquisition and processing, and troubleshooting and service.

• facilitate alignment and future collaboration with scripps research.

contact :

please send the cv by email attachment to the dr. shen:

email subject: the title of the position for which you are applying.

for more details on szbl and our research, please visit our website:

email content: please include your contact information, name, telephone number, and any dates on which you would be unavailable for an interview. upon request, applications will be considered confidentially.

compound management lead candidate

the position

this position will require the successful candidate to start a compound management group from the ground up. a strong background in compound management is required. he/she will establish a workflow for sample request and fulfillment, select appropriate lab automation and software, receive requests for samples, track, coordinate, and perform order fulfillment and distribution of both solids, solutions, and plates to scientists.

education and experience:

• bachelor's degree in engineering, biochemistry, chemistry or related field

• 5+ years experience the in a compound management, high throughput screening and/or lab automation

• a proven track record managing a group.

• experience with liquid handling equipment and other laboratory automation technology systems. experience with the span-8 liquid handlers (e.g. tecan evo, hamilton star), acoustic dispensers, plate transfer devices and related experience.

• proven track record of evaluating, selection, implementation of lab equipment and software and the generation of sops.

• experience with lims and inventory management software.

the activities of the compound management group include, but are not limited to, those shown below. applicants should have experience in all the following:

• manual handling of all incoming compounds; including powder weighing, dissolution, and plating.

• handle logistical aspects of compound management; including sample inventory tracking and storage and ensure accurate record keeping.

• responsible for uploading data to compound registry, curation of registry, and managing data workflow.

• prioritize and communicate timelines; provide progress updates to the group.

• weighing and preparing compounds and solutions

• arraying compounds from vials to microtiter plates

• re-array compound plates

• maintaining and tracking compound library database

• provide support for sample receiving/sorting services, plate generation, screening, inventory maintaining and qc support using various liquid handling instruments for compound management.

• provide liquid handling performance monitoring services and other laboratory equipment maintenance per customer sops.

• keep accurate data entry of all activities in tracking database.

• provide operational flexibility by cross-training across all job functions with other team members.

• carefully follow customer sop’s, orders, and schedules.

proposed salary and benefit:$70k-100k/y

purpose of the initial working period (6 months) at calibr, scripps research:

• help assemble the key compound libraries for ultra hts that fit the best need of the new institute in shenzhen

• get trained with the appropriate lab automation and software

• familiarize with the workflow of sample requests and fulfillment, track, coordinate, and perform order fulfillment and distribution of both solids, solutions, and plates to scientists and cro vendors

• build-up first-hand experience in daily operation and maintenance, library maintenance and replenishment and troubleshooting and service.

contact:

please send the cv by email attachment to the dr. shen:

email subject: the title of the position for which you are applying.

for more details on szbl and our research, please visit our website:

email content: please include your contact information, name, telephone number, and any dates on which you would be unavailable for an interview. upon request, applications will be considered confidentially.

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